Curriculum vitae

I completed my medical degree in New Zealand and began my ophthalmology training in the UK as a Senior House Officer at the Sussex Eye Hospital, Brighton. I then took a Senior House Officer job at St Thomas' Hospital in London and went on to complete a retinal PhD at The Rayne Institute, St Thomas' Hospital. Following that I undertook a further four years of Registrar training based at Moorfields Eye Hospital, where I stayed on as a Vitreoretinal Fellow. I now work as a Consultant Ophthalmic Surgeon at King's College Hospital, a large teaching hospital in South London. I undertake cataract surgery and have a sub-specialty interest in macular and retinal surgery. I am an Honorary Senior Lecturer and continue my research at The Rayne Institute, now part of King's College London (University of London). My research interests and peer reviewed publications are given below. Current interests include studies of ocular macromolecular diffusion and drug modification in relation to the pharmacotherapy of age-related macular degeneration, and ocular safety testing using cell culture techniques. In addition, I am Editor of the Moorfields Manual of Ophthalmology. I am currently UK Chief Investigator for the CABERNET study of epimacular brachytherapy, a new surgical treatment for wet age-related macular degeneration developed by NeoVista, and the MERITAGE study investigating the use of this device in patients who require frequent anti-VEGF (Lucentis/Avastin) therapy. I am Chief Investigator of a large (n 363) UK randomised controlled trial of epimacular brachytherapy called MERLOT, which is supported via the National Institute for Health Research (NIHR) Comprehensive Clinical Research Network (CCRN). The CABERNET and MERITAGE studies are now closed to recruitment. Further information for patients interested in joining the MERLOT study is available by visiting the MERLOT website (www.merlotstudy.com). Collaborative links include The School of Pharmacy (London), King's College London Physics Department, King's College London Neurosciences Division (IoP), Southampton Health Technology Assessments Centre, Queens University Belfast (Central Angiographic Reading Centre), University Eye Hospital Tubingen (Retinal Implant), and others. Active research grants are in excess of £1.3M, from national charitable research institutions and industry.

TEXTBOOKS

1. Jackson TL. Editor-in-Chief, Moorfields Manual of Ophthalmology. Elsevier (Mosby), London 2008 [for details click here].

2. Jackson TL, Egan C, Bird AC. Chapter 10. Medical Retina, Moorfields Manual of Ophthalmology. Ed. Jackson TL. Elsevier, London 2008.

3. Jackson TL, Da Cruz LD, Gregor Z. Chapter 11. Surgical Retina, Moorfields Manual of Ophthalmology. Ed. Jackson TL. Elsevier, London 2008.

4. Bates A, Jackson TL, Adams GGW. Chapter 12. Paediatric Ophthalmology. Moorfields Manual of Ophthalmology. Ed. Jackson TL. Elsevier, London 2008.

5. Jackson TL Chapter 11. Vital staining and retinal detachment surgery. Vital Dyes in Vitreoretinal Surgery: Chromovitrectomy. Ed. Meyer CH. Developments in Ophthalmology, Karger, Bonn 2008.

6. Jackson TL. Indocyanine green accused: the case for and against ICG assisted macular surgery. British Journal of Ophthalmology 2005;89:395-396. [Editorial]

7. Stanescu-Segall D, Jackson TL. Vital staining with indocyanine green: a review of the clinical and experimental studies relating to safety . Eye 2009;23:504-18 [Perspective]

8. Jackson TL, Eykyn SJ, Graham EM, Stanford MR. Endogenous bacterial endophthalmitis: A 17 year prospective series and review of 267 reported cases. Survey of Ophthalmology 2003; 48: 403-423 [Major Review].

9. Jackson TL, Vote B, Knight BC, El Amir A, Stanford MR, Marshall J. Safety testing of infracyanine green using retinal pigment epithelium and glial cell cultures. Investigative Ophthalmology and Visual Science 2004;45:3697-3703.

10a.Jackson TL, Hillenkamp J, Knight B, Zhang, JJ, Thomas D, Stanford MR, Marshall J. Safety testing of indocyanine green and trypan blue using retinal pigment epithelium and glial cell cultures. Investigative Ophthalmology and Visual Science 2004;45:2778-2785

10b. Jackson TL Safety testing of indocyanine green and trypan blue using retinal pigment epithelium and glial cell cultures. Investigative Ophthalmology and Visual Science Online. December 30, 2004 [Author comment].

11. Jackson TL. Safety of indocyanine green as a vital stain. Anesthesiology 2004;100;1330 [Letter].

12. Saikia P, Maisch T, Kobuch K, Jackson TL, Bäumler W, Szeimies RM, Gabel VP, Hillenkamp J. Safety testing of indocyanine green in an ex vivo porcine retina model. Investigative Ophthalmology and Visual Science 2006;47:4998-5003.

13. Jackson TL, Griffin L, Vote B, Hillenkamp J, Marshall J. An experimental method for testing novel retinal vital stains. Experimental Eye Research 2005; 81:446-454.

14. Jackson TL, Marshall J. Fluorophore assisted retinal break detection using antibodies to glial fibrillary acidic protein. Investigative Ophthalmology and Visual Science 2004;45:993-1001.

15. Jackson TL, Kwan A, Laidlaw DAH, Aylward GW. Identification of retinal breaks using subretinal trypan blue injection. Ophthalmology 2007;114:587-590 .

16. Jackson TL, Hillenkamp J, Williamson TH, Clarke KW, Almubarak AI, Marshall J. An experimental model of rhegmatogenous retinal detachment: surgical results and glial cell response. Investigative Ophthalmology and Visual Science 2003; 44:4026-4034.

17. Jackson TL, Antcliff RJ, Hillenkamp J, Marshall J. Human retinal molecular weight exclusion limit and estimate of species variation. Investigative Ophthalmology and Visual Science 2003; 44:2141-2146.

18. Jackson TL, Hussain A, Noury AMS, Hodgets A, Hillenkamp J, Sullivan PM, Marshall J. Human scleral hydraulic conductivity: age-related changes, topographical variation, and potential scleral outflow facility. Investigative Ophthalmology and Visual Science 2006;47:4942-4946.

19. Jackson TL, Hussain A, Morley AMS, Sullivan PM, Hodgetts A, El-Osta A, Hillenkamp J, Charles SJ, Sheard R, Williamson TH, Kumar A, Laidlaw DAH, Woon HW, Costen MJ, Luff AJ, Marshall J. Scleral hydraulic conductivity and macromolecular diffusion in patients with uveal effusion syndrome. Investigative Ophthalmology and Visual Science 2008;49:5033-40.

20. Anderson OA, Jackson TL, Singh JK, Hussain AA, Marshall J. Human transscleral albumin permeability and the effect of topographical location and donor age. Investigative Ophthalmology and Visual Science 2008;49:4041-5.

21. Hillenkamp J, Hussain AA, Jackson TL, Cunningham JR, Marshall J. The influence of pathlength and matrix components on ageing characteristics of transport between the choroid and the outer retina. Investigative Ophthalmology and Visual Science 2004;45:1493-1498.

22. Hillenkamp J, Hussain AA, Jackson TL, Cunningham JR, Marshall J. Compartmental analysis of taurine transport to the outer retina in bovine eyes Investigative Ophthalmology and Visual Science 2004;45;4099-4105.

23. Hillenkamp J, Hussain AA, Jackson TL, Cunningham JR, Marshall J. Taurine uptake by human retinal pigment epithelium: implications for the transport of small solutes between the choroid and the outer retina. Investigative Ophthalmology and Visual Science 2004;45;4529-4534.

24. Hillenkamp J, Hussain AA, Jackson TL, Cunningham JR, Marshall J. Effect of taurine and apical potassium concentration on electrophysiologic parameters of bovine retinal pigment epithelium. Experimental Eye Research. 2006; 82:258-264.

25. Jackson TL, Ong GL, MacIndoe MA, Ripley LG. Monocular chromatic discrimination threshold and achromatic contrast sensitivity in children born prematurely. American Journal of Ophthalmology 2003;136:710-719.

26. Jackson TL, Ong GL, Ripley LG. Orientational contrast sensitivity and chromatic contrast thresholds in multiple sclerosis. American Journal of Ophthalmology. 2004; 137:283-286.

27. Newsom RSB, Ong GL, Jackson TL, Ripley LG, Fisher M, Casswell TG. Screening for CMV retinitis using chromatic discrimination thresholds and achromatic contrast sensitivity. British Journal of Ophthalmology 2000;84:877-880.

29. Jackson TL, Williamson TH. Amikacin retinal toxicity. British Journal of Ophthalmology 1999;83(10):1199-1200 [Letter].

30. Jackson TL, Meacock W, Graham EM. Severe intraocular inflammation after a change of HAART. British Journal of Ophthalmology 2000;84:933-934 [Letter]

31. Jackson TL, Thiagarajan M, Murthy R, Snead MP, Wong D, Williamson TH. Pupil block glaucoma in phakic and pseudophakic patients after vitrectomy with silicone oil injection. American Journal of Ophthalmology. 2001;132:414-416

32. Jackson TL, Thiagarajan M, Murthy R, Snead MP, Wong D, Williamson TH. Pupil block glaucoma in phakic and pseudophakic patients after vitrectomy with silicone oil injection. American Journal of Ophthalmology. 2002;134:634-635 [Author comment]

33. Jackson TL, Larson J, Tanner V, Williamson TH. Combined phacoemulsification cataract extraction and pars plana vitrectomy without intraocular lens implant. Ophthalmologica 2001;215:271-275.

34. Tanner V, Chauhan DS, Jackson TL, Williamson TH. Optical coherence tomography of the vitreoretinal interface in macular hole formation. British Journal of Ophthalmology 2001;85:1092-1097

35. Hillenkamp J, Kraus J, Framme C, Jackson TL, Roider J, Gabel VP, Sachs HG. Retreatment of full-thickness macular hole: predictive value of optical coherence tomography. British Journal of Ophthalmology 2007;91:1445-1449.

36. Jackson T, Tanner V, Williamson TH. Modified sutureless sclerotomies in pars plana vitrectomy. American Journal of Ophthalmology 2000;129:116-117 [Letter].

37. Wang M, Zhang JJ, Jackson TL, Sun X, Wu W, Marshall J. Safety and efficacy of intracapsular tranilast microspheres in experimental posterior capsule opacification. Journal of Cataract and Refractive Surgery 2007;33:2122-2128.

38. Jackson TL, Beun L. A prospective study of cost, patient satisfaction and outcome of treatment of chalazion by medical and nursing staff. British Journal of Ophthalmology 2000;84:782-785.

39. Jackson TL, Farmer CKT, Kingswood C, Vickers S. Hypotensive ischemic optic neuropathy and peritoneal dialysis. American Journal of Ophthalmology 1999;128:109-111.

COMMISIONED ARTICLES

40. Ramkissoon YD, Jackson TL, Charteris DG. Managing common retinal disorders. Practitioner 2006; 250: 1-4.

PUBLISHED ABTRACTS

Anderson O, Jackson TL, Hussain AA, Marshall. Human trans-scleral albumin diffusion and effect of cryopreservation. ARVO abstract 2006.

Jackson TL, Griffin L, Vote B, Hillenkamp, Marshall J. A systematic experimental method of screening novel retinal vital stains. ARVO abstract 2005.

Anderson O, Jackson TL, Hussain AA, Marshall J. Human trans-scleral albumin diffusion and effect of cryopreservation. ARVO abstract 2005.

Hillenkamp JM, Hussain AA, Jackson TL, Cunningham JR, Marshall J. Effect of Taurine and apical potassium concentration on eletrophysiology of bovine retinal pigment epithelium ARVO abstract 2005.

Hillenkamp JM, Hussain AA, Jackson TL, Cunningham JR, Constable P, Marshall J. Transepithelial transport of taurine across isolated bovine retinal pigment epithelium. ARVO abstract 2004.

Hillenkamp JM, Hussain AA, Zhang JJ, Jackson TL, Cunningham JR, Marshall J. Age-related macular degeneration: metabolic insufficiency in the ageing retina? ARVO abstract 2003.

Jackson TL, Hillenhamp J, El Osta A, Zhang JJ, Marshall J. Safety testing of indocyanine green and trypan blue using a cell culture model. ARVO abstract 2003.

Jackson TL, Marshall J. Fluorophore assisted retinal break detection: In vivo studies using Cy3 tagged antibody to glial fibrillary acidic protein. ARVO abstract 2002.

Jackson TL, Antcliff RJ, Hodgetts A, Hussain AA, Hillenkamp J, Zhang JJ, Marshall. Retinal exclusion limit: species variation. ARVO abstract 2001.

Noury AM, Jackson TL, Hodgetts A, Marshall J. Hydraulic conductivity of sclera as a function of age. ARVO abstract 2001.

Hillenkamp J, Cunningham JR, Chauhan D, Jackson TL, Hussain AA, Zhang JJ, Marshall J: Diffusion of Taurine across bovine Bruch`s membrane and choroid. ARVO abstract 2001.

Jackson TL, Eykyn S, Stanford M, Graham E. Endogenous bacterial endophthalmitis, a diagnostic pitfall: 20 years experience at St Thomas’ Hospital and review of 230 reported cases. Fed Infect Dis 2000.

Jackson TL, Ong GL, Pearson AR, Ripley LG. Orientational contrast sensitivity in patients with multiple sclerosis. ARVO abstract 1999.

Ong GL, Newsom RSB, Jackson TL, Coldrick I, Ripley LG, Fisher M, Casswell AG. Achromatic and chromatic discrimination sensitivity in HIV patients with and without CMV retinitis. ARVO abstract 1998.

Jackson TL, Ong GL, Ripley LG, Hughes P. An experimental evaluation of optic nerve function in multiple sclerosis patients undergoing controlled aerobic exercise with a constant core body temperature. ARVO abstract 1998.

Poon WKM, Ong GL, Jackson TL, Ripley LG, Casswell AG. Chromatic discrimination can be used to predict the outcome of macular hole surgery. ARVO abstract 1997.

Jackson TL, Moate BJR, Knowles PJ, Ong GL, Poon WKM, Tregear SJ, Ripley LG, Casswell AG. Chromatic and achromatic contrast sensitivity in patients with HIV infection. ARVO abstract 1997.

Pearson AR, Tregear SJ, Jackson TL, Harden AF, Ripley LG. Therapeutic levels of digoxin do not affect chromatic discrimination threshold. ARVO abstract 1996.